HILIC Silica HPLC Column | Polar Compound Separation

HILIC Silica HPLC Column

HILIC (Hydrophilic Interaction Liquid HPLC COLUMN) is a separation mode achieved through the partitioning of polar solutes from high concentration, water-miscible, organic mobile phase into hydrophilic surface environment.

Description

Product Introduction

HILIC silica columns are designed to retain highly polar organic molecules that cannot be retained by reversed-phase HPLC COLUMN due to their high polarity. Unlike reversed-phase separation, which uses a high propor- tion of aqueous phase to retain polar molecules, HILIC silica columns use highly volatile mobile phases (>80% organic phase), which is ideal for mass spectrometry response and detection sensitivity.


Features

1. Unique chemical bonding technology provides the surface of the HILIC stationary phase with acidic, neutral, and basic characteristics.

2. High chemical stability with low stationary phase loss.

3. Suitable for the separation of polar drugs, peptides, amino acids, and other compounds.


Specifications

pH Range2.0-8.0
Particle Size3μm, 5μm, 10μm
Surface Area(m2/g)320(120Å)
Carbon Loading(%)N/A
USP ListL3
EndcappedNo


Ordering Information—HILIC Silica

Particle SizeID (mm)Column Length (mm)
150200250
3μm 120 Å4.6YZHHS46150-3YZHHS46200-3YZHHS46250-3
5μm 120 Å4.6YZHHS46150-5YZHHS46200-5YZHHS46250-5
10μm 120 Å4.6YZHHS46150-10YZHHS46200-10YZHHS46250-10

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