C3 HPLC Columns – Ideal for Protein & Peptide Separations

LP-C3 HPLC Column

LP is abbreviation for Low pH. LP phases are designed for use at low pH conditions. LP phase consists of two very bulky hydrophobic protective groups to prevent siloxane bond from hydrolysis at low pH condition. So LP column is extremely stable in very low pH mobile phase and at high temperature, even at the lowest pH of 1.0, making it the most stable phase for low pH application in the market.Because it is not endcapped and has more surface silanols, LP phase has more retention for some early eluted polar compounds, and provides different selectivities.


Description

Product Introduction

LP-C3 column utilizes a patented, unique, single functional group silane with larger isopropyl side chain groups, protecting the silicon-oxygen-carbon bonds on the critical silica surface to prevent carbon chain hydrolysis and degradation under low pH conditions. To ensure longer column lifespan and optimal reproducibility during separations at low pH conditions (down to pH 1), the column is left un-capped. This column can withstand 100% aqueous to 100% organic phases. The high-purity, low-acidity silica gel provides excellent peak shapes for acidic, basic, and neutral compounds, making it the preferred choice for method development under low pH mobile phase conditions.


Specifications

pH Range1.0-8.0
Particle Size5μm
Surface Area(m2/g)320(120Å)
Carbon Loading(%)4(120Å)
USP ListL56
EndcappedNo


Ordering Information—LP-C3

Bonded phaseID (mm)Column Length (mm)

LP-C3

5μm 120 Å

4.6
150200250
YZHC3L46150-5YZHC3L46200-5YZHC3L46250-5

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